Description

(S)-(+)-2-Methoxy-2-(1-Naphthyl)Propionic Acid is a high-purity, single-enantiomer chiral carboxylic acid derivative, serving as a critical chiral resolving agent and synthetic building block. Its primary value lies in its ability to separate enantiomers of amines and other basic compounds, which is fundamental for producing optically pure pharmaceuticals and agrochemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, fine chemical, and advanced material sectors who require high stereochemical fidelity.

Application

• Chiral Resolution Agent: Widely used for the enantiomeric separation of racemic amines and other basic pharmaceuticals via diastereomeric salt formation.
• Pharmaceutical Intermediate: Acts as a key chiral auxiliary or precursor in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Analytical Chemistry Standard: Employed as a reference standard in HPLC and chiral chromatography methods for method development and validation.
• Catalyst and Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Fine Chemical Synthesis: Serves as a building block for synthesizing complex, optically active molecules in agrochemical and specialty chemical research.
• Academic & Industrial R&D: A valuable tool for studying stereoselective reactions and developing new chiral methodologies.

Basic Information

Product Name	(S)-(+)-2-Methoxy-2-(1-Naphthyl)Propionic Acid
CAS No.	102691-93-0
Molecular Formula	C₁₅H₁₆O₃
Molecular Weight	244.29 g/mol
Synonyms	(S)-(+)-2-Methoxy-2-(1-Naphthyl)Propanoic Acid; (S)-2-Methoxy-2-(1-Naphthyl)Propionic Acid; (S)-α-Methoxy-α-(1-naphthyl)propionic Acid; (S)-Methoxy(1-naphthyl)acetic Acid Methyl Derivative; (S)-MNAP; (S)-1-Naphthylmethoxyacetic Acid Methyl Ester Derivative; (S)-O-Methyl Mandelic Acid 1-Naphthyl Derivative; L-Methoxy(1-naphthyl)acetic Acid Methyl Derivative
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Methoxy-2-(1-Naphthyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for chiral synthesis and resolution. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and specific impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (ee)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.