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N(Alpha)-3-(4-Hydroxyphenylpropionyl)Asparaginyl-Lysyl-(N(Epsilon)-4-Azidobenzoyl)Threoninamide CAS NO 102604-64-8


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CAS No.:102604-64-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N(Alpha)-3-(4-Hydroxyphenylpropionyl)Asparaginyl-Lysyl-(N(Epsilon)-4-Azidobenzoyl)Threoninamide is a specialized, high-purity synthetic peptide derivative designed for advanced research and development. This compound is critical for applications requiring precise molecular conjugation, leveraging its photoreactive azido group for cross-linking and labeling studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on proteomics, drug discovery, and the development of novel bioconjugates.

Application

  • Bioconjugation & Cross-linking Agent: Used as a key intermediate for attaching biomolecules (e.g., proteins, antibodies) to surfaces, polymers, or other molecules via photoaffinity labeling.
  • Proteomics Research: Employed in the study of protein-protein interactions, protein structure, and function through targeted covalent modification.
  • Drug Discovery & Development: Serves as a building block or linker in the synthesis of peptide-based therapeutics and targeted drug delivery systems.
  • Diagnostic Reagent Development: Utilized in the creation of sensitive immunoassays and diagnostic probes where stable, site-specific labeling is required.
  • Material Science & Biomaterials: Applied in the functionalization of biomaterial surfaces to enhance biocompatibility or create bioactive coatings.
  • Chemical Biology Tools: Acts as a critical reagent for developing activity-based probes to study enzyme function and metabolic pathways.

Basic Information

Product Name N(Alpha)-3-(4-Hydroxyphenylpropionyl)Asparaginyl-Lysyl-(N(Epsilon)-4-Azidobenzoyl)Threoninamide
CAS No. 102604-64-8
Molecular Formula C30H38N8O9
Molecular Weight 654.67 g/mol
Synonyms N(Alpha)-3-(4-Hydroxyphenylpropionyl)-Asparaginyl-Lysyl-(N(Epsilon)-4-Azidobenzoyl)-Threoninamide; 4-Azidobenzoyl-Thr-Asn-Lys Peptide Derivative; Photoactivatable Peptide Crosslinker; Azido-Phenylalanine Containing Peptide; Hpp-Asp-Lys(Nε-4-Azidobenzoyl)-Thr-NH2; CAS 102604-64-8; Hpp-Asn-Lys(4-AzBz)-Thr-NH2
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Quality Control

Our N(Alpha)-3-(4-Hydroxyphenylpropionyl)Asparaginyl-Lysyl-(N(Epsilon)-4-Azidobenzoyl)Threoninamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC-MS) Conforms to structure
Purity (HPLC) ≥ 95%
Assay (Peptide Content) ≥ 80%
Water Content (KF) ≤ 5.0%
Single Impurity (HPLC) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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