Description

3Beta-Hydroxy-5-Cholestene 3-Hemisuccinate Tris Salt is a high-purity, chemically modified sterol derivative, serving as a critical intermediate and reference standard in advanced biochemical research and pharmaceutical development. Its primary value lies in its defined structure and purity, enabling precise studies of cholesterol metabolism, membrane biophysics, and the synthesis of more complex steroid conjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, well-characterized building blocks for drug discovery, diagnostic assay development, and metabolic pathway analysis.

Application

• Pharmaceutical Intermediate: Key starting material or precursor in the synthesis of novel steroid-based therapeutics and diagnostic agents.
• Biochemical Research: Used as a reference standard and substrate in studies of cholesterol biosynthesis, transport, and esterification pathways.
• Lipidomics & Analytical Standards: Serves as a high-purity internal standard or calibrant in LC-MS, GC-MS, and HPLC analyses for accurate quantification of sterols and related metabolites.
• Membrane Biology Studies: Employed to investigate cholesterol's role in membrane fluidity, lipid raft formation, and protein-lipid interactions.
• Enzyme Assay Substrate: Potential substrate for studying the activity of enzymes like sterol O-acyltransferases or other modifying enzymes.
• Diagnostic Reagent Manufacturing: Component in the formulation of calibration kits and reagents for clinical diagnostics related to lipid metabolism.

Basic Information

Product Name	3Beta-Hydroxy-5-Cholestene 3-Hemisuccinate Tris Salt
CAS No.	102601-49-0
Molecular Formula	C31H49O6 · 3(C4H11N)
Molecular Weight	Contact for details
Synonyms	Cholesteryl Hemisuccinate Tris Salt; Tris(2-amino-2-hydroxymethyl-propane-1,3-diol) Salt of Cholesteryl Hemisuccinate; Tris Salt of Cholesterol Hemisuccinate; 3β-Hydroxycholest-5-ene 3-hemisuccinate tris salt; Tris(hydroxymethyl)aminomethane salt of Cholesteryl hydrogen succinate; Tris-ammonium salt of Cholesteryl hemisuccinate; Tris buffer salt of Cholesterol hemisuccinate
EINECS	Contact for details

Quality Control

Our 3Beta-Hydroxy-5-Cholestene 3-Hemisuccinate Tris Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.