Description

Cytosine Arabinoside 5'-Triphosphate, Sodium Salt is a high-purity nucleotide analog triphosphate essential for biochemical and pharmaceutical research. This compound serves as a critical substrate and chain terminator in enzymatic reactions, particularly for DNA polymerases and reverse transcriptases. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, virology, and oncology drug development for studies involving nucleic acid synthesis, antiviral mechanisms, and cancer therapeutics.

Application

• Substrate for Enzymatic Studies: Used as a substrate for DNA-dependent and RNA-dependent DNA polymerases in kinetic and mechanistic research.
• Antiviral Research: Critical component in studies investigating the mechanism of action of nucleoside analog drugs, particularly against viral polymerases.
• Oncology Research: Employed in biochemical assays to study the metabolism and incorporation of cytarabine (Ara-C) triphosphate, a key chemotherapeutic agent, into DNA.
• Chain Termination in Sequencing: Acts as a chain-terminating nucleotide in specialized in vitro DNA synthesis and sequencing applications.
• Biochemical Reagent: Serves as a high-purity standard and reagent in diagnostic kit development and quality control testing for related pharmaceuticals.
• Metabolic Pathway Analysis: Used to trace and analyze the anabolic pathways of nucleoside analogs within cellular systems.

Basic Information

Product Name	Cytosine Arabinoside 5'-Triphosphate, Sodium Salt
CAS No.	102601-42-3
Molecular Formula	C9H14N3O14P3Nan (n≈3)
Molecular Weight	Approx. 585.1 (Free acid), Contact for exact salt form weight.
Synonyms	Ara-CTP; 1-β-D-Arabinofuranosylcytosine 5'-triphosphate sodium salt; Cytarabine triphosphate sodium salt; Cytosine-β-D-arabinofuranoside 5'-triphosphate sodium salt; 1-β-D-Arabinofuranosyl-4-amino-2(1H)-pyrimidinone 5'-triphosphate sodium salt; Ara-C Triphosphate Na Salt; 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone 5'-triphosphate sodium salt.
EINECS	Contact for details.

Quality Control

Our Cytosine Arabinoside 5'-Triphosphate, Sodium Salt is manufactured under strict quality systems suitable for research and diagnostic applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure high batch-to-batch consistency and reliability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥95%
Water Content (KF)	≤5%
Biological Activity	Functional as substrate for polymerase enzymes

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.