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S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol CAS NO 102490-05-1
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CAS No.:102490-05-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol is a high-purity, chiral binaphthol derivative widely recognized as a versatile and effective ligand and catalyst precursor in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in a range of critical organic transformations, enabling the production of single-enantiomer compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance chiral auxiliaries for creating optically active intermediates and active ingredients.
Application
- As a chiral ligand for asymmetric metal-catalyzed reactions, including hydrogenation, Diels-Alder, and aldol additions.
- As a precursor for constructing chiral phosphoric acid catalysts used in organocatalysis.
- In the synthesis of enantiomerically pure pharmaceutical intermediates, such as those for cardiovascular and central nervous system drugs.
- For the development of novel chiral materials and polymers with specific optical properties.
- In academic and industrial R&D for methodological development in stereoselective synthesis.
- As a resolving agent or chiral selector in chromatographic separations.
Basic Information
| Product Name | S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol |
| CAS No. | 102490-05-1 |
| Molecular Formula | C32H22O2 |
| Molecular Weight | 438.52 g/mol |
| Synonyms | (S)-3,3'-Diphenyl-1,1'-bi-2-naphthol; (S)-3,3'-Diphenyl-[1,1'-binaphthalene]-2,2'-diol; (S)-3,3'-Diphenyl-BINOL; (S)-3,3'-Ph2-BINOL; S-BINOL Derivative; S-3,3'-Diphenyl-1,1'-bi-2-naphthol; (S)-(-)-3,3'-Diphenyl-2,2'-dihydroxy-1,1'-binaphthyl |
| EINECS | Contact for details |
Quality Control
Our S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for chiral auxiliaries in advanced synthesis. Certificates of Analysis (COA) providing detailed results for assay, enantiomeric excess (ee), and impurity profiles are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and optical purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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