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S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol CAS NO 102490-05-1


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CAS No.:102490-05-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol is a high-purity, chiral binaphthol derivative widely recognized as a versatile and effective ligand and catalyst precursor in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in a range of critical organic transformations, enabling the production of single-enantiomer compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance chiral auxiliaries for creating optically active intermediates and active ingredients.

Application

  • As a chiral ligand for asymmetric metal-catalyzed reactions, including hydrogenation, Diels-Alder, and aldol additions.
  • As a precursor for constructing chiral phosphoric acid catalysts used in organocatalysis.
  • In the synthesis of enantiomerically pure pharmaceutical intermediates, such as those for cardiovascular and central nervous system drugs.
  • For the development of novel chiral materials and polymers with specific optical properties.
  • In academic and industrial R&D for methodological development in stereoselective synthesis.
  • As a resolving agent or chiral selector in chromatographic separations.

Basic Information

Product Name S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol
CAS No. 102490-05-1
Molecular Formula C32H22O2
Molecular Weight 438.52 g/mol
Synonyms (S)-3,3'-Diphenyl-1,1'-bi-2-naphthol; (S)-3,3'-Diphenyl-[1,1'-binaphthalene]-2,2'-diol; (S)-3,3'-Diphenyl-BINOL; (S)-3,3'-Ph2-BINOL; S-BINOL Derivative; S-3,3'-Diphenyl-1,1'-bi-2-naphthol; (S)-(-)-3,3'-Diphenyl-2,2'-dihydroxy-1,1'-binaphthyl
EINECS Contact for details

Quality Control

Our S-3,3'-Bis(Phenyl)-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for chiral auxiliaries in advanced synthesis. Certificates of Analysis (COA) providing detailed results for assay, enantiomeric excess (ee), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and optical purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Enantiomeric Excess (HPLC) ≥ 99.0% ee
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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