Description

(R)-n-Deacetyl Colchicine D-10-Camphorsulfonate is a high-purity chiral derivative of colchicine, specifically designed for advanced pharmaceutical research and development. This compound is critical for studying tubulin polymerization inhibition and serves as a key intermediate or reference standard in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and contract research organizations (CROs) focused on oncology, anti-inflammatory, and anti-gout drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel colchicine analogs and other bioactive molecules.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the mechanisms of microtubule dynamics and cell cycle inhibition.
• Drug Discovery & Development: Serves as a lead compound or precursor for developing new therapeutic agents targeting cancer and inflammatory diseases.
• Academic Research: Utilized in university and institutional labs for pharmacological and chemical biology studies.

Basic Information

Product Name	(R)-n-Deacetyl Colchicine D-10-Camphorsulfonate
CAS No.	102419-97-6
Molecular Formula	C31H39NO9S
Molecular Weight	601.71 g/mol
Synonyms	(R)-N-Deacetylcolchicine 10-Camphorsulfonate; (R)-Deacetylcolchicine Camphorsulfonate Salt; (R)-DAC Camphorsulfonate; (7R)-N-Deacetylcolchicine (1S)-10-Camphorsulfonate; Colchicine derivative D-10-CSA; (R)-Deacetylcolchicine D-10-CSA; (R)-N-Deacetylcolchicine D-10-Camphorsulfonic Acid Salt
EINECS	Contact for details

Quality Control

Our (R)-n-Deacetyl Colchicine D-10-Camphorsulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.