Description

N6-([6-Aminohexyl]Carbamoyl-Methyl)Adenosine 5'-Triphosphate Lithium Salt is a chemically modified nucleotide analog, specifically engineered with a reactive aminohexyl linker arm. This compound is critical for researchers and developers requiring a stable, high-energy phosphate donor that can be covalently attached to surfaces or biomolecules. It is primarily utilized in advanced life science research and diagnostic assay development. The product is supplied as a lithium salt to enhance its stability and solubility in aqueous buffers.

Application

• Enzyme Kinetics & Labeling: Acts as a substrate or cofactor for kinases and other ATP-utilizing enzymes, often used in activity assays and enzyme immobilization.
• Bioconjugation & Probe Synthesis: The primary amino group on the linker facilitates covalent coupling to carboxylated surfaces, carrier proteins, or other molecules for creating detection probes.
• Diagnostic Assay Development: Used in the manufacture of chemiluminescent, fluorescent, or colorimetric diagnostic kits, particularly for high-sensitivity immunoassays and nucleic acid detection.
• ATP-Analog Studies: Serves as a non-hydrolyzable or modified ATP analog in mechanistic studies of ATPases, motor proteins, and signal transduction pathways.
• Affinity Chromatography: Can be immobilized on resin for the purification of ATP-binding proteins or enzymes.
• Cellular Energy Research: Investigated in studies related to cellular energy metabolism and nucleotide signaling when a tagged version is required.

Basic Information

Product Name	N6-([6-Aminohexyl]Carbamoyl-Methyl)Adenosine 5'-Triphosphate Lithium Salt
CAS No.	102185-24-0
Molecular Formula	C18H30N7O13P3 • xLi
Molecular Weight	Approx. 705.4 (free acid) + x(6.94)
Synonyms	6-N-(6-Aminohexyl)carbamoylmethyl-ATP lithium salt; Amino-C6-ATP, Li salt; N6-(6-Aminohexyl)carbamoylmethyladenosine-5'-triphosphate lithium salt; 6-[(6-Aminohexyl)amino]-6-oxohexanoyl-ATP; ATP-ε-Ahx; Biotinylation-grade ATP analog; Reactive ATP derivative; Etheno-ATP analog (related class).
EINECS	Contact for details

Quality Control

Our production of N6-([6-Aminohexyl]Carbamoyl-Methyl)Adenosine 5'-Triphosphate Lithium Salt adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by multiple analytical techniques, including HPLC for purity assessment and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and assay is provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for critical research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term stability, it is recommended to store under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Assay (UV)	≥ 90% (as ATP analog)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.