Description

Adenosine 5'-Triphosphate Periodateoxidized Borohydride is a chemically modified derivative of ATP, a fundamental energy currency in biological systems. This compound is critical for research and development in biochemistry and molecular biology, where it serves as a stable, non-hydrolyzable ATP analog for studying enzyme kinetics and nucleotide-dependent processes. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on signal transduction and metabolic pathway analysis.

Application

• Enzyme Inhibition Studies: Used as a substrate analog to investigate the mechanisms of ATP-dependent enzymes like kinases and ATPases.
• Biochemical Assay Development: Serves as a key component in the formulation of high-throughput screening (HTS) assays for drug discovery.
• Diagnostic Reagents: Employed in the production of specialized diagnostic kits for monitoring cellular energy status and related pathologies.
• Signal Transduction Research: Essential for studying G-protein coupled receptors (GPCRs) and other nucleotide-sensitive signaling pathways.
• Metabolic Research: Acts as a tool compound to probe metabolic flux and energy metabolism in cell culture and tissue models.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Adenosine 5'-Triphosphate Periodateoxidized Borohydride
CAS No.	102185-15-9
Molecular Formula	C10H17N5O13P3 (Base structure of ATP, modified)
Molecular Weight	Approx. 580 g/mol (Contact for exact calculated weight)
Synonyms	Periodate-Oxidized ATP; ATP Periodateoxidized Borohydride; ATP Dialdehyde Reduced with Borohydride; Modified ATP; Non-hydrolyzable ATP Analog; ATPoxBor; Adenosine-5'-triphosphate periodateoxidized, borohydride reduced
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Triphosphate Periodateoxidized Borohydride is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and NMR, are validated to meet the exacting standards of the pharmaceutical and life science research industries.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity Test	Inhibits standard ATPase activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.