Description

3-Aminopyridine Adenine Dinucleotide Phosphate, Sodium is a chemically modified analog of the essential coenzyme NADP+, featuring a 3-aminopyridine substitution. This modification is critical for its role as a potent and selective inhibitor of NADP+-dependent enzymes, making it a valuable tool for probing enzymatic mechanisms and metabolic pathways. It is primarily utilized by researchers and developers in pharmaceutical discovery, biochemical research, and diagnostic assay development.

Application

• Enzymology Research: As a specific inhibitor for mechanistic studies of NADP+-dependent dehydrogenases, reductases, and other oxidoreductases.
• Pharmaceutical Screening: Used in high-throughput assays to identify potential drug candidates that target NADP+-binding sites or related metabolic pathways.
• Metabolic Pathway Analysis: A key reagent for investigating the pentose phosphate pathway, fatty acid synthesis, and antioxidant defense systems involving NADPH.
• Diagnostic Kit Development: Employed in the formulation of specialized diagnostic reagents for clinical chemistry analyzers.
• Biochemical Probe: Serves as a molecular probe to study enzyme kinetics, coenzyme binding affinity, and allosteric regulation.
• Academic & Industrial R&D: Essential for basic research in universities and applied research in biotechnology companies.

Basic Information

Product Name	3-Aminopyridine Adenine Dinucleotide Phosphate, Sodium
CAS No.	102047-37-0
Molecular Formula	C21H26N7O17P3Na•xH2O
Molecular Weight	Approx. 801.36 (Anhydrous)
Synonyms	3-Aminopyridine NADP+, Sodium Salt; 3-AP-NADP+; 3-Amino-Pyridine Adenine Dinucleotide Phosphate; AADP; NADP+ 3-Aminopyridine Analog; 3-Pyridinamine Adenine Dinucleotide Phosphate; Coenzyme NADP+ 3-Aminopyridine Derivative; 3-APADP
EINECS	Contact for details

Quality Control

Our 3-Aminopyridine Adenine Dinucleotide Phosphate, Sodium is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term stability, it is recommended to store desiccated. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0%
Absorbance Ratio (A260/A280)	2.0 - 2.2
Biological Activity (Enzymatic Assay)	Conforms (Inhibitory activity confirmed)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.