Description

n-Cbz-Ala-Arg-Arg 4-Methoxy-β-Naphthylamide Acetate Salt is a specialized synthetic peptide derivative designed as a chromogenic substrate for enzymatic assays. This compound matters for its high specificity in detecting and quantifying the activity of proteolytic enzymes, particularly trypsin and trypsin-like enzymes, which is critical for biochemical research and diagnostic development. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent industries for enzyme kinetics studies, inhibitor screening, and assay development.

Application

• Enzyme Substrate for Protease Assays: A highly specific chromogenic substrate for the detection and kinetic analysis of trypsin, thrombin, and related serine proteases.
• Biochemical Research & Development: Used in academic and industrial R&D for studying enzyme mechanisms, inhibition, and protein-protein interactions.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for clinical analysis of pancreatic function and coagulation disorders.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential protease inhibitor drug candidates.
• Quality Control in Bioprocessing: Monitors protease activity during the production and purification of biopharmaceuticals to ensure product consistency and purity.

Basic Information

Product Name	n-Cbz-Ala-Arg-Arg 4-Methoxy-β-Naphthylamide Acetate Salt
CAS No.	102047-33-6
Molecular Formula	C₃₈H₅₆N₁₂O₉ • xC₂H₄O₂
Molecular Weight	Contact for details
Synonyms	CBZ-Ala-Arg-Arg-4-Methoxy-2-Naphthylamide Acetate; Z-Ala-Arg-Arg-4-Methoxy-β-NA Acetate; Benzyloxycarbonyl-Ala-Arg-Arg-4-Methoxy-β-Naphthylamide Acetate; Ala-Arg-Arg 4-Methoxy-β-NA, N-Cbz protected; Trypsin Substrate; Chromogenic Trypsin Substrate; Protease Substrate 102047-33-6
EINECS	Contact for details

Quality Control

Our n-Cbz-Ala-Arg-Arg 4-Methoxy-β-Naphthylamide Acetate Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Conforms (as trypsin substrate)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.