Description

Adenylyl-(2'→5')-Cytidinemonoammonium Salt (9Ci) is a chemically defined dinucleotide monophosphate derivative, specifically an ammonium salt of the 2'-5' linked adenylyl-cytidine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a building block and a potential intermediate in the synthesis of oligonucleotides and nucleoside analogs. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in molecular biology, antiviral research, and the development of novel therapeutic agents.

Application

• Oligonucleotide Synthesis: Serves as a key intermediate or building block in the chemical and enzymatic synthesis of specialized oligonucleotides with 2'-5' linkages.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving nucleotidyltransferases, polymerases, and RNA-modifying enzymes.
• Antiviral Research: Investigated for its potential role in studying the 2-5A (2',5'-oligoadenylate) pathway, which is part of the innate immune response to viral infection.
• Pharmaceutical Development: Acts as a precursor or reference compound in the research and development of nucleoside-based therapeutics and prodrugs.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents for molecular diagnostics and probe development.
• Life Science Standards: Used to prepare high-purity analytical standards for quality control and method validation in nucleotide analysis.

Basic Information

Product Name	Adenylyl-(2'→5')-Cytidinemonoammonium Salt (9Ci)
CAS No.	102029-84-5
Molecular Formula	C19H27N8O12P2 • xNH3
Molecular Weight	Contact for details
Synonyms	2'-5' Adenylylcytidine Ammonium Salt; pppA2'p5'C Ammonium Salt; 2',5'-Oligoadenylate Derivative; Adenosine(2'→5')cytidine triphosphate ammonium salt; A2'p5'C; 2-5A-Core Dimer Ammonium Salt; 5'-O-[(5'-O-Phosphonatoadenosin-2'-O-yl)phosphonato]cytidine Ammonium Salt
EINECS	Contact for details

Quality Control

Our Adenylyl-(2'→5')-Cytidinemonoammonium Salt is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.