Description

8-(6-Aminohexyl)Amino-Adenosine 5'-Monophosphate Lithium Salt is a chemically modified nucleotide monophosphate derivative, designed for advanced biochemical and pharmaceutical research. This compound is valued for its role as a potent and selective activator of adenosine monophosphate-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis. It is primarily utilized by researchers and developers in the fields of metabolic disease research, drug discovery, and molecular biology, where precise modulation of AMPK signaling is critical.

Application

• Biochemical Research: As a specific activator of AMPK for studying metabolic pathways, cellular energy sensing, and signal transduction mechanisms.
• Pharmaceutical Development: A key reference standard and intermediate in the discovery and development of novel therapeutics targeting metabolic disorders such as type 2 diabetes and obesity.
• Enzyme Studies: Used in in vitro assays to investigate AMPK kinetics, substrate specificity, and inhibitor screening.
• Cell Biology: Applied in cell culture models to induce and study AMPK-mediated effects on autophagy, mitochondrial biogenesis, and glucose/lipid metabolism.
• Academic Research: A critical tool for universities and research institutes exploring the fundamental biology of energy balance and its implications in aging and disease.

Basic Information

Product Name	8-(6-Aminohexyl)Amino-Adenosine 5'-Monophosphate Lithium Salt
CAS No.	102029-82-3
Molecular Formula	C16H27LiN8O7P
Molecular Weight	481.29 g/mol
Synonyms	8-(6-Aminohexyl)amino-AMP Li Salt; 8-(6-Aminohexylamino)-AMP Lithium Salt; AICAR 8-(6-Aminohexyl)amino Derivative; AMPK Activator Compound; 8-(6-Aminohexylamino)adenosine 5'-monophosphate lithium; 8-N-(6-Aminohexyl)adenosine-5'-monophosphoric acid lithium salt; 5'-AMP, 8-[(6-aminohexyl)amino]-, lithium salt; 102029-82-3
EINECS	Contact for details

Quality Control

Our 8-(6-Aminohexyl)Amino-Adenosine 5'-Monophosphate Lithium Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (AMPK Activation)	Reported EC50 value provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.