Description

Adenosine 3':5'-Cyclic Monophosphate Tris Salt is a high-purity biochemical reagent, a stable salt form of the critical second messenger cyclic AMP (cAMP). This compound is essential for fundamental research into intracellular signal transduction pathways, including those regulating metabolism, gene expression, and cell proliferation. It is a vital raw material and reference standard for pharmaceutical R&D, diagnostic assay development, and life science research across global markets.

Application

• Pharmaceutical Research & Development: As a key intermediate and reference standard in drug discovery programs targeting G-protein-coupled receptors (GPCRs) and protein kinase A (PKA) pathways.
• Diagnostic Assay Manufacturing: Used in the production of ELISA kits, chemiluminescent immunoassays, and other in vitro diagnostic (IVD) reagents for clinical testing.
• Cell Biology & Biochemistry Studies: Fundamental research tool for studying cAMP-mediated cellular processes, including hormone action, neuronal signaling, and cardiac function.
• Enzymology & Protein Kinase Assays: Serves as a substrate and activator in enzymatic studies, particularly for assaying adenylate cyclase and protein kinase A activity.
• Academic & Institutional Research: Critical reagent for universities and research institutes conducting basic science in molecular biology, physiology, and pharmacology.
• Biochemical Production: Potential use as a starting material or additive in the synthesis of more complex nucleotides or specialized cell culture media.

Basic Information

Product Name	Adenosine 3':5'-Cyclic Monophosphate Tris Salt
CAS No.	102029-77-6
Molecular Formula	C10H12N5O6P · C4H11NO3
Molecular Weight	491.33 g/mol
Synonyms	Cyclic AMP Tris Salt; cAMP Tris Salt; Adenosine 3',5'-cyclic monophosphate tris salt; 3',5'-Cyclic AMP Tris Salt; cAMP Sodium Salt (related form); Adenosine cyclic 3',5'-(hydrogen phosphate) tris salt; A-cyclic 3',5'-monophosphate Tris salt; NSC 94017 (Tris salt form)
EINECS	Contact for details

Quality Control

Our Adenosine 3':5'-Cyclic Monophosphate Tris Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and endotoxins where required. Certificates of Analysis (COA) are provided, detailing batch-specific results and confirming compliance with relevant specifications for research and in vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
pH (1% Solution)	7.0 - 9.0
Optical Rotation	Specific rotation provided per COA
Endotoxin (where specified)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.