Description

Sialyl-Fucosyl-Lacto-n-Norhexaosylceramide is a complex, biologically significant glycosphingolipid, specifically a ganglioside. This compound matters as a high-purity biochemical standard and research reagent, essential for advancing studies in glycobiology, immunology, and cell signaling. It is primarily needed by research institutions, diagnostic developers, and pharmaceutical companies engaged in biomarker discovery, vaccine development, and the study of cell membrane interactions and cancer biology.

Application

• Biochemical Research Standard: Used as a reference standard in mass spectrometry, HPLC, and TLC for the identification and quantification of complex gangliosides in biological samples.
• Glycobiology Studies: Critical for investigating carbohydrate-protein interactions, cell adhesion processes, and the role of specific glycan structures in cellular recognition.
• Immunology & Vaccine Development: Serves as a potential antigen or hapten in the research and development of vaccines and therapeutic antibodies targeting specific glycan epitopes.
• Diagnostic Reagent Development: Employed in the development of diagnostic assays and kits for detecting antibodies or lectins specific to sialylated and fucosylated glycan structures.
• Cell Signaling & Oncology Research: Used to study the role of gangliosides in cell growth, differentiation, apoptosis, and metastasis, particularly in cancer research.
• Neuroscience Research: Applied in studies of neural development, synaptic function, and neurodegenerative diseases where ganglioside composition is crucial.

Basic Information

Product Name	Sialyl-Fucosyl-Lacto-n-Norhexaosylceramide
CAS No.	101359-93-7
Molecular Formula	C86H151N3O41
Molecular Weight	~1842.16 g/mol
Synonyms	IV3Neu5Ac,III4Fuc-nLc6Cer; Sialyl Lewis x pentaglycosylceramide (sLex); Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ1-4Glcβ1-1'Cer; Lacto-N-fucopentaose VI ceramide, sialyl-; HSO-828; Sialyl Lex ganglioside; Sialylated Lewis X glycosphingolipid; Monosialyl Lewis X hexaglycosylceramide
EINECS	Contact for details

Quality Control

Our Sialyl-Fucosyl-Lacto-n-Norhexaosylceramide is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques, including NMR and mass spectrometry, to confirm structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere or desiccated conditions to maintain stability. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in Chloroform/Methanol/Water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.