Description

4-Epichlortetracycline Hydrochloride is a key chemical intermediate and derivative of the tetracycline class of antibiotics. This compound is of significant importance for research and development in pharmaceutical synthesis, particularly for studying antibiotic structure-activity relationships and developing novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis and structural modification of tetracycline-based antibiotics.
• Biochemical Research: Used in studies investigating antibiotic mechanisms of action, bacterial resistance, and the biochemical pathways of tetracycline derivatives.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, specialized tetracycline analogs for experimental purposes.

Basic Information

Product Name	4-Epichlortetracycline Hydrochloride
CAS No.	101342-45-4
Molecular Formula	C22H23ClN2O8 • HCl
Molecular Weight	515.34 g/mol
Synonyms	4-Epichlortetracycline HCl; 4-Epichlortetracycline Hydrochloride; 4-Epichloro-7-chlortetracycline Hydrochloride; 4-Epi-CTC HCl; (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-7-chloro-2-naphthacenecarboxamide Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Epichlortetracycline Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with standards relevant for research and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.