Description

Methyl Salicylate β-D-o-Glucuronide Triacetate Methyl Ester CAS NO 101231-54-3 is a high-purity, synthetically derived chemical intermediate, specifically a protected glucuronide derivative of methyl salicylate. This compound is critical for researchers and manufacturers requiring a stable, well-characterized precursor for advanced synthesis and analytical method development. It is primarily utilized in pharmaceutical R&D, analytical chemistry, and the production of specialized fine chemicals.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantification and identification of salicylate metabolites in bioanalytical studies and pharmacokinetic research.
• Metabolic Pathway Research: Used as a key intermediate in studying the glucuronidation pathways of salicylate-based drugs and natural products.
• Advanced Organic Synthesis: Acts as a protected building block for the synthesis of more complex glucuronidated molecules or prodrugs in medicinal chemistry.
• Analytical Method Development: Employed to validate and calibrate analytical techniques such as HPLC, LC-MS, and NMR for detecting glucuronide conjugates.
• Biochemical Tool Compound: Utilized in enzymology studies to investigate the activity and specificity of UDP-glucuronosyltransferase (UGT) enzymes.

Basic Information

Product Name	Methyl Salicylate β-D-o-Glucuronide Triacetate Methyl Ester
CAS No.	101231-54-3
Molecular Formula	C₂₁H₂₆O₁₂
Molecular Weight	470.42 g/mol
Synonyms	Methyl 2-[(2-Methoxy-2-oxoethyl)oxy]benzoate 2,3,4-Tri-O-acetyl-β-D-glucopyranuronate Methyl Ester; Methyl Salicylate Glucuronide Triacetate Methyl Ester; Methyl (2-Methoxy-2-oxoethyl) 2,3,4-Tri-O-acetyl-β-D-glucopyranosiduronate; Salicylic Acid Methyl Ester Glucuronide Triacetate; β-D-Glucopyranuronic Acid, 2-[(Methoxycarbonyl)phenoxy]-, 1-Methyl Ester, 2,3,4-Triacetate
EINECS	Contact for details

Quality Control

Our Methyl Salicylate β-D-o-Glucuronide Triacetate Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.