Description

1-Hexadecanoylglycol-2-Phosphocholine is a synthetic phospholipid derivative, a key structural analog of lysophosphatidylcholine. This compound matters as a high-purity biochemical tool and a critical intermediate for advanced lipid research and formulation. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing drug delivery systems, studying membrane biophysics, and creating specialized lipid-based products.

Application

• Liposome & Nanoparticle Formulation: A crucial building block for constructing stable liposomal vesicles and lipid nanoparticles (LNPs) used in targeted drug delivery and mRNA vaccine technology.
• Biochemical Research: Serves as a standard, substrate, or model membrane component in studies of phospholipase activity, lipid metabolism, and cell signaling pathways.
• Cell Culture & Transfection Reagents: Used as an excipient or active component in specialized media and reagents to enhance membrane permeability and cellular uptake.
• Pharmaceutical Intermediates: Acts as a key synthetic precursor for more complex therapeutic phospholipids and prodrugs.
• Biomimetic Material Science: Incorporated into coatings, sensors, and matrices to impart biomimetic, surface-active, or self-assembly properties.
• Analytical Reference Standard: Employed as a high-purity certified reference material (CRM) for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-Hexadecanoylglycol-2-Phosphocholine
CAS No.	101056-77-3
Molecular Formula	C26H54NO7P
Molecular Weight	523.68 g/mol
Synonyms	16:0 Lyso PC; 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine; Palmitoyl Lysophosphatidylcholine; Lyso-PC(16:0/0:0); 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; L-α-Lysopalmitoylphosphatidylcholine; sn-Glycero-3-phosphocholine 1-hexadecanoate; LysoPPC
EINECS	Contact for details

Quality Control

Our 1-Hexadecanoylglycol-2-Phosphocholine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and cGMP-grade manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (argon or nitrogen), please contact us. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.