Description

H-Ala-Ala-Phe-4M-β-Na is a specialized, modified tripeptide derivative designed for advanced research and development applications. This compound is valued for its role as a key intermediate or substrate in enzymatic studies and proteomics research, offering precise molecular functionality. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on peptide chemistry, enzyme kinetics, and novel therapeutic discovery.

Application

• Enzymology Research: Used as a specific chromogenic or fluorogenic substrate for studying the activity and inhibition of proteolytic enzymes like chymotrypsin or subtilisin.
• Protease Assay Development: Serves as a critical component in high-throughput screening (HTS) assays to identify and characterize novel protease inhibitors for drug discovery.
• Biochemical Tool Compound: Employed in mechanistic studies to understand substrate specificity and catalytic mechanisms of serine and other classes of proteases.
• Peptide Synthesis Intermediate: Acts as a building block for the synthesis of more complex peptide analogs or conjugates in medicinal chemistry programs.
• Diagnostic Reagent Formulation: Potential use in the development of specialized diagnostic kits for detecting specific enzymatic activities in clinical or research samples.

Basic Information

Item	Details
Product Name	H-Ala-Ala-Phe-4M-β-Na
CAS No.	100900-09-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ala-Ala-Phe 4-Methoxy-β-naphthylamide; L-Alanyl-L-alanyl-L-phenylalanine 4-methoxy-2-naphthylamide; Suc-Ala-Ala-Phe-AMC (related analog); AAPF-4MβNA; Protease Substrate III; Chymotrypsin Substrate 4MβNA; N-Succinyl-Ala-Ala-Phe-4-methoxy-2-naphthylamide (common parent compound); Tripeptide 4-methoxy-β-naphthylamide derivative
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Phe-4M-β-Na is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.