Description

Biotinyl-Adenoside Diphosphate is a specialized biochemical reagent that combines the vitamin biotin with adenosine diphosphate (ADP). This compound is critical for research and development in enzymology and molecular biology, serving as a high-affinity ligand or substrate analog. It is primarily utilized by scientists and manufacturers in the pharmaceutical, diagnostic, and life science research sectors for studying biotin-dependent enzymes and developing sensitive assay systems.

Application

• Enzyme Research & Characterization: Used as a substrate or inhibitor in studies of biotin-dependent carboxylases, such as acetyl-CoA carboxylase and pyruvate carboxylase.
• Diagnostic Kit Development: Serves as a key component in the formulation of ELISA and other immunoassay kits for detecting biotinylated molecules.
• Affinity Chromatography: Immobilized on solid supports for the purification of streptavidin, avidin, and biotin-binding proteins.
• Metabolic Pathway Analysis: Employed in biochemical assays to investigate ATP-ADP conversion cycles and energy metabolism in cellular systems.
• Pharmaceutical Screening: Acts as a tool compound in high-throughput screening (HTS) campaigns to identify modulators of biotin-utilizing enzymes.
• Bioconjugation & Probe Synthesis: Used as a precursor for synthesizing advanced biotinylated probes and tags for cellular imaging and detection.

Basic Information

Product Name	Biotinyl-Adenoside Diphosphate
CAS No.	100844-62-0
Molecular Formula	C₂₀H₂₉N₇O₁₃P₂S
Molecular Weight	669.50 g/mol
Synonyms	Biotin-ADP; Biotinylated Adenosine Diphosphate; N-Biotinyl-5'-adenosine Diphosphate; 5'-O-[Hydroxy({[hydroxy({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl] Adenosine Biotinyl Ester; Biotinyl Adenosine 5'-Diphosphate; ADP-Biotin
EINECS	Contact for details

Quality Control

Our Biotinyl-Adenoside Diphosphate is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.