Description

Corticosterone 21-Sulfate Potassium is a sulfated metabolite of corticosterone, a key glucocorticoid hormone. This water-soluble conjugate is primarily utilized as a critical reference standard and analytical reagent in steroid metabolism research and diagnostic assay development. It is essential for scientists and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors who require high-purity materials for method validation and quantitative analysis.

Application

• Biomedical Research Standard: Serves as a primary reference standard for studying corticosterone metabolism, sulfation pathways, and steroid hormone regulation.
• Diagnostic Assay Development: Used in the calibration and validation of immunoassays (e.g., ELISA, RIA) and LC-MS/MS methods for the accurate quantification of steroid sulfates in biological matrices.
• Pharmaceutical Impurity Profiling: Employed as a known impurity or metabolite standard in the quality control of corticosteroid-based drug products.
• Endocrinology Studies: A vital tool for investigating the role of sulfated steroids in various physiological and pathological processes, including stress response and endocrine disorders.
• Biomarker Discovery: Used in metabolomics and biomarker research to understand disease states related to adrenal function and steroid dysregulation.

Basic Information

Product Name	Corticosterone 21-Sulfate Potassium
CAS No.	100775-23-3
Molecular Formula	C21H29KO8S
Molecular Weight	480.61 g/mol
Synonyms	Corticosterone 21-Sulfate Potassium Salt; 11β,21-Dihydroxypregn-4-ene-3,20-dione 21-Sulfate Potassium; Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, 21-(hydrogen sulfate), potassium salt (1:1); Corticosterone 21-(Hydrogen Sulfate) Potassium; 21-Sulfocortexone Potassium; Corticosterone Sulfate K+
EINECS	Contact for details

Quality Control

Our Corticosterone 21-Sulfate Potassium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and quality standards. The product is suitable for use as a high-purity analytical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.