Description

2-Deoxy-2-(3-Hydroxytetradecanoyl)Aminoglucose 6-Phosphate is a key phosphorylated sugar derivative and a crucial intermediate in the biosynthesis of lipid A, the membrane anchor of lipopolysaccharides (LPS) in Gram-negative bacteria. This compound matters for researchers and manufacturers developing novel antibiotics, vaccine adjuvants, and immunomodulatory agents targeting bacterial endotoxin pathways. It is essential for biochemical research, pharmaceutical development, and high-purity synthesis in the life sciences sector.

Application

• Biochemical Research: A critical substrate and intermediate for studying the lipid A biosynthetic pathway and bacterial endotoxin assembly.
• Pharmaceutical Development: Used in the research and synthesis of novel antibiotics and antimicrobial agents targeting Gram-negative bacteria.
• Immunology & Vaccine Adjuvant Research: Serves as a precursor for synthesizing defined lipid A structures to study innate immune responses and develop next-generation vaccine adjuvants.
• Enzymology Studies: Acts as a specific substrate for enzymes like LpxA and other transferases involved in the Raetz pathway.
• Metabolic Pathway Analysis: Utilized in tracing and understanding bacterial metabolism related to cell wall and membrane biosynthesis.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Item	Detail
Product Name	2-Deoxy-2-(3-Hydroxytetradecanoyl)Aminoglucose 6-Phosphate
CAS No.	100759-95-3
Molecular Formula	C20H38NO11P
Molecular Weight	499.49 g/mol
Synonyms	UDP-2,3-diacylglucosamine; Lipid X precursor; 2-Deoxy-2-[(3R)-3-hydroxytetradecanamido]-D-glucopyranose 6-(dihydrogen phosphate); D-Glucose, 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-, 6-(dihydrogen phosphate); Aminoglucose 6-phosphate derivative; LPS biosynthetic intermediate; UDP-2,3-diacyl-GlcN
EINECS	Contact for details

Quality Control

Our 2-Deoxy-2-(3-Hydroxytetradecanoyl)Aminoglucose 6-Phosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.