Description

7,8,13,13A-Tetradehydro-2,3,11-Trimethoxyberbinium Chloride is a high-purity, specialized alkaloid derivative with significant research and development potential. This compound matters as a key intermediate and reference standard for pharmaceutical discovery, particularly in the study of bioactive natural products and their synthetic analogs. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel berberine analogs and other isoquinoline alkaloids for pharmacological screening.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Biochemical Research: Employed in studies investigating the biological activity, mechanism of action, and structure-activity relationships (SAR) of protoberberine-type compounds.
• Academic Research: A valuable reagent for synthetic organic chemistry projects and natural product chemistry studies in university and institutional laboratories.
• Fine Chemical Synthesis: Acts as a building block for the custom synthesis of more complex molecules for specialized applications.

Basic Information

Product Name	7,8,13,13A-Tetradehydro-2,3,11-Trimethoxyberbinium Chloride
CAS No.	19717-36-3
Molecular Formula	C21H20NO4+ Cl-
Molecular Weight	385.84 g/mol
Synonyms	2,3,11-Trimethoxy-7,8,13,13a-tetradehydroberbinium Chloride; 7,8,13,13a-Tetradehydro-2,3,11-trimethoxyberbinium Chloride; Dehydrocorydaline Chloride; NSC 339586; 13,13a-Didehydro-2,3,10-trimethoxyberbinium Chloride (alternate numbering); Tetradehydrocorydaline Chloride; Berbinium, 7,8,13,13a-tetradehydro-2,3,11-trimethoxy-, chloride
EINECS	Contact for details

Quality Control

Our 7,8,13,13A-Tetradehydro-2,3,11-Trimethoxyberbinium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 97.0% (on dried basis)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.