Description

Protoberberine CAS NO 19716-69-9 is a key isoquinoline alkaloid and a fundamental structural class for numerous bioactive compounds found in nature. Its significance lies in its role as a versatile chemical intermediate and a pharmacologically active scaffold for research and development. This product is essential for pharmaceutical R&D laboratories, nutraceutical manufacturers, and academic institutions focused on developing new therapeutic agents, particularly in areas like metabolic health and antimicrobial applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of various berberine analogs and other isoquinoline-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and a core structure in studies investigating mechanisms of action for metabolic regulation, antimicrobial activity, and neurological effects.
• Nutraceutical Development: Employed in the research and formulation of advanced dietary supplements targeting metabolic syndrome and gut health.
• Academic & Industrial R&D: A fundamental building block for medicinal chemistry programs aiming to discover novel therapeutics with improved efficacy and safety profiles.
• Reference Material: Utilized in analytical laboratories for method development and quality control of herbal extracts and finished products containing protoberberine alkaloids.

Basic Information

Product Name	Protoberberine
CAS No.	19716-69-9
Molecular Formula	C₂₀H₁₈NO₄⁺
Molecular Weight	336.36 g/mol
Synonyms	Protoberberinium; 5,6-Dihydrodibenzo[a,g]quinolizinium; Dihydroberberine; Tetrahydrojatrorrhizine; 13-Methylprotoberberine; Berberine, dihydro-; NSC 169865; Protoberberine cation
EINECS	Contact for details

Quality Control

Our Protoberberine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development purposes. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.