Description

(-)-Vallesamidine is a specific enantiomer of the indole alkaloid vallesamidine, identified by CAS NO 19637-77-5. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its complex stereochemistry and biological activity profile. It serves as a valuable chiral building block and reference standard for researchers in medicinal chemistry and natural product synthesis, particularly for developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Acts as a key chiral intermediate or reference standard in the synthesis of novel bioactive molecules and potential drug candidates.
• Medicinal Chemistry Studies: Used to investigate structure-activity relationships (SAR) and for biological screening against various targets.
• Natural Product Synthesis: Serves as a sophisticated building block in the total synthesis of complex indole alkaloids and related natural products.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new enantioselective synthetic methodologies.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories (HPLC, GC, LC-MS).
• Biochemical Research: Used in studies exploring enzyme interactions and metabolic pathways involving alkaloid structures.

Basic Information

Product Name	(-)-Vallesamidine
CAS No.	19637-77-5
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	(3S,15S,19S)-Ibogamine-18-carboxylic acid methyl ester; Vallesamidine; (-)-Vallesamidine; (3β,19α)-Ibogamine-18-carboxylic acid methyl ester; NSC 169854; Methyl (19S)-ibogamine-18-carboxylate
EINECS	Contact for details

Quality Control

Our (-)-Vallesamidine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.