Description

n-Nitrosocytisine is a specialized nitrosamine derivative of the alkaloid cytisine. This compound is of significant interest in advanced chemical research and development, particularly for its role as a key intermediate or reference standard. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on analytical chemistry, toxicology studies, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis and study of more complex alkaloid derivatives and pharmaceutical candidates.
• Analytical Reference Standard: Used as a high-purity standard in chromatographic analysis (HPLC, GC-MS) for method development, validation, and quality control testing.
• Toxicology and Safety Studies: Employed in research investigating the formation, detection, and metabolic pathways of nitrosamine impurities, which are a key focus in regulatory compliance for pharmaceuticals.
• Biochemical Research: Utilized in studies exploring nicotinic acetylcholine receptor (nAChR) interactions and related neurological pathways, given its structural relationship to cytisine.
• Process Chemistry Development: Acts as a model compound or intermediate in optimizing synthetic routes and scaling up production processes for specialized fine chemicals.

Basic Information

Product Name	n-Nitrosocytisine
CAS No.	19634-60-7
Molecular Formula	C₁₁H₁₃N₃O₂
Molecular Weight	219.24 g/mol
Synonyms	N-Nitrosocytisine; Cytisine, N-nitroso-; 1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 3-nitroso-; 3-Nitrosocytisine; (-)-N-Nitrosocytisine; (1R,5S)-3-Nitrosocytisine
EINECS	Contact for details

Quality Control

Every batch of n-Nitrosocytisine is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay purity, impurity profiles, and physical characteristics. Our quality systems are designed to support research and development requiring high-integrity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.