Description

Batrachotoxinin A is a highly potent steroidal alkaloid and the core pharmacophore of the batrachotoxin family of neurotoxins. This compound is of significant interest in advanced biochemical and pharmacological research due to its specific and powerful action as a voltage-gated sodium channel activator. It serves as a critical reference standard and research tool for neuroscientists, toxicologists, and pharmaceutical developers studying ion channel function, neurotoxin mechanisms, and potential therapeutic targets.

Application

• Neuroscience Research: Used as a precise pharmacological tool to study the function and modulation of voltage-gated sodium channels in neuronal signaling.
• Toxicology Studies: Acts as a key reference standard for the identification, quantification, and mechanistic investigation of batrachotoxin and related natural toxins.
• Drug Discovery & Development: Employed in high-throughput screening and target validation assays for discovering novel analgesics, anesthetics, or neuroprotective agents that interact with sodium channels.
• Biochemical Assays: Serves as a critical reagent in in vitro studies to understand ligand-receptor interactions and signal transduction pathways involving ion channels.
• Academic & Pharmaceutical R&D: Essential for basic research in university and industrial laboratories focused on neuropharmacology and membrane biophysics.

Basic Information

Product Name	Batrachotoxinin A
CAS No.	19457-37-5
Molecular Formula	C24H35NO5
Molecular Weight	417.54 g/mol
Synonyms	Batrachotoxinin A; Batrachotoxinin; 3α,9α-Epoxy-14β,18β-(epoxyethano-N-methylimino)-5β-pregna-7,16-diene-3β,11α,20α-triol 20α-(2,4-dimethyl-1H-pyrrole-5-carboxylate); Batrachotoxin A; BTX-A; Batrachotoxinin A alcohol
EINECS	Contact for details

Quality Control

Our Batrachotoxinin A is produced and handled under strict quality protocols to ensure the highest standards of purity and consistency required for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry best practices for high-purity reference standards to guarantee reliable and reproducible results in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.