Description

L-α-Lysophosphatidylcholine, Stearoyl is a high-purity, single-chain phospholipid derivative where the sn-1 position is esterified with stearic acid. This compound is a critical biochemical tool and functional excipient, valued for its superior membrane permeability and emulsifying properties compared to its diacyl counterparts. It is essential for researchers and formulators in advanced pharmaceutical development, particularly in drug delivery systems, and for manufacturers of high-end nutraceuticals and cosmetic actives.

Application

• Liposomal & Nanoparticle Drug Delivery: A key component for creating unilamellar vesicles with enhanced stability and encapsulation efficiency for hydrophobic and hydrophilic actives.
• Biochemical Research: Used as a substrate or effector in studies of phospholipase activity, cell signaling pathways (e.g., involving LPA), and membrane biophysics.
• Pharmaceutical Excipient: Serves as a potent solubilizer and permeation enhancer in injectable and topical formulations to improve bioavailability.
• Nutraceutical Formulations: Employed in advanced supplement delivery systems for ingredients like CoQ10 and fat-soluble vitamins to increase absorption.
• Cosmetic Actives: Functions as a skin-identical lipid to restore barrier function and as a carrier for active ingredients in anti-aging and restorative skincare products.
• Cell Culture & Media Supplement: Used in specialized serum-free media formulations to support the growth of certain cell lines.

Basic Information

Product Name	L-α-Lysophosphatidylcholine, Stearoyl
CAS No.	19420-57-6
Molecular Formula	C₂₆H₅₄NO₇P
Molecular Weight	539.68 g/mol
Synonyms	1-Stearoyl-2-hydroxy-sn-glycero-3-phosphocholine; LysoPC(18:0); 1-Stearoyl-sn-glycero-3-phosphocholine; Lysophosphatidylcholine 18:0; L-α-Lysophosphatidylcholine, stearoyl; LPC(18:0/0:0); sn-Glycero-3-phosphocholine, 1-stearoyl derivative
EINECS	243-090-1

Quality Control

Our L-α-Lysophosphatidylcholine, Stearoyl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 10 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.