Description

1-Oleoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a lysophosphatidylcholine (LPC), that serves as a critical building block and functional excipient in advanced life science applications. Its value lies in its role as a key component for constructing liposomes and lipid nanoparticles, enabling the encapsulation and delivery of active pharmaceutical ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries developing next-generation drug delivery systems and membrane model studies.

Application

• Lipid Nanoparticle (LNP) Formulation: A crucial structural lipid for creating stable LNPs used in mRNA and siRNA delivery systems.
• Liposome Preparation: Acts as a fusogenic agent or a component in liposomal bilayers for drug encapsulation and targeted delivery.
• Cell Membrane Research: Used in biochemistry and biophysics to study membrane fluidity, permeability, and protein-lipid interactions.
• Pharmaceutical Excipient: Serves as a solubilizing and emulsifying agent in injectable formulations and topical products.
• Biomimetic Coatings: Employed in the development of sensor surfaces and diagnostic assays that mimic natural cell membranes.
• Cosmetic Actives Carrier: Enhances the penetration and stability of active ingredients in high-performance skincare formulations.

Basic Information

Product Name	1-Oleoyl-Sn-Glycero-3-Phosphocholine
CAS No.	19420-56-5
Molecular Formula	C26H52NO7P
Molecular Weight	521.67 g/mol
Synonyms	LPC(18:1/0:0); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphocholine; LysoPC(18:1); Lysophosphatidylcholine 18:1; Oleoyl lysophosphatidylcholine; sn-Glycero-3-phosphocholine, 1-oleoyl derivative; (2R)-2-Hydroxy-3-(trimethylammonio)propyl (9Z)-octadec-9-enoate phosphate
EINECS	243-094-0

Quality Control

Our 1-Oleoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or colorless viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.