Description

3Beta, 5Beta-Tetrahydroaldosterone is a key reduced metabolite of the mineralocorticoid hormone aldosterone. This compound is of significant value as a high-purity reference standard and an important intermediate in steroid research and pharmaceutical development. It is primarily required by research institutions, pharmaceutical companies, and diagnostic manufacturers engaged in endocrinology studies, analytical method development, and the synthesis of related steroid compounds.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of aldosterone metabolites in research and quality control laboratories.
• Biochemical Research: Serves as a critical intermediate or substrate in studies investigating aldosterone metabolism, enzyme activity (e.g., 5β-reductase), and mineralocorticoid receptor pathways.
• Diagnostic Kit Development: Employed in the development and calibration of immunoassays and LC-MS/MS kits for the clinical measurement of steroid hormone profiles.
• Metabolite Synthesis: Acts as a precursor in the organic synthesis of more complex steroid derivatives and labeled analogs (e.g., deuterated standards) for mass spectrometry.
• Academic Research: Utilized in university and institutional labs for endocrinology, pharmacology, and physiology studies related to blood pressure regulation and electrolyte balance.

Basic Information

Product Name	3Beta, 5Beta-Tetrahydroaldosterone
CAS No.	19360-15-7
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	3β,5β-Tetrahydroaldosterone; 5β-Tetrahydroaldosterone; 3β,5β-THA; 18,11-Hemiacetal of 3β,5β,21-trihydroxy-20-oxopregnane-18-carboxaldehyde; 11β,21-Dihydroxy-3,20-dioxo-5β-pregnane-18-carboxaldehyde, cyclic 18,11-hemiacetal; Aldosterone, 3β,5β-tetrahydro-; 5β-Pregnane-3β,11β,21-triol-18,20-dione, cyclic 18,11-hemiacetal
EINECS	Contact for details

Quality Control

Our 3Beta, 5Beta-Tetrahydroaldosterone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Quality is assured through techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.