Description

N6-(1,2-Dicarboxyethyl)-Amp is a specialized biochemical derivative of adenosine monophosphate (AMP), characterized by the addition of a dicarboxyethyl moiety at the N6 position. This structural modification is significant for its role as a key intermediate in the synthesis of advanced nucleotide analogs and for its utility in biochemical research and pharmaceutical development. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide chemistry, enzyme studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel nucleotide-based drugs and prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenylate kinases and other ATP-related enzymes.
• Nucleotide Analog Development: Acts as a precursor for creating modified nucleotides with altered biological activity for research applications.
• Diagnostic Reagent Synthesis: Employed in the development of specialized reagents for molecular diagnostics and assay systems.
• Enzyme Mechanism Probes: Utilized to investigate the binding sites and catalytic mechanisms of enzymes that interact with adenosine derivatives.

Basic Information

Product Name	N6-(1,2-Dicarboxyethyl)-Amp
CAS No.	19240-42-7
Molecular Formula	C12H17N5O10P
Molecular Weight	422.27 g/mol
Synonyms	N6-(1,2-Dicarboxyethyl)adenosine 5'-monophosphate; N6-Carboxyethyl-AMP; N6-(1,2-Dicarboxyethyl)-AMP; N6-(1,2-Dicarboxyethyl)adenosine monophosphate; 1,2-Dicarboxyethyl-AMP; Adenosine-5'-monophosphate, N6-(1,2-dicarboxyethyl)-; AMP, N6-(1,2-dicarboxyethyl)-
EINECS	Contact for details

Quality Control

Our N6-(1,2-Dicarboxyethyl)-Amp is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be aligned with specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.