Description

Creatinine Hydrochloride is the hydrochloride salt form of creatinine, a key nitrogenous organic compound. This high-purity derivative is essential for ensuring precise and reliable results in diagnostic and research applications. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, clinical diagnostics, and life science sectors for calibration, standardization, and method development.

Application

• Clinical Diagnostic Reagents: A critical primary standard and raw material for calibrating and validating assays that measure creatinine levels in blood and urine, a vital indicator of kidney function.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method validation in drug development and manufacturing.
• Biochemical Research: Serves as a fundamental reagent in metabolic studies, enzyme kinetics research, and investigations into muscle metabolism and renal physiology.
• In-Vitro Diagnostics (IVD): A key component in the production of control solutions, calibrators, and test kits for automated clinical chemistry analyzers.
• Method Development & Validation: Employed by analytical laboratories to develop, optimize, and verify new testing protocols for creatinine detection (e.g., HPLC, enzymatic methods).

Basic Information

Product Name	Creatinine Hydrochloride
CAS No.	19230-81-0
Molecular Formula	C4H8ClN3O
Molecular Weight	149.58 g/mol
Synonyms	2-Amino-1-methyl-4,5-dihydro-1H-imidazol-5-one hydrochloride; 1-Methylglycocyamidine hydrochloride; Creatinine HCl; Creatinine monohydrochloride; 1-Methyl-2-iminoimidazolidin-4-one hydrochloride; 1-Methylhydantoin-2-imide hydrochloride
EINECS	242-904-1

Quality Control

Our Creatinine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for use as a reference material. Certificates of Analysis (COA) with detailed test results are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
pH (5% solution)	3.0 - 5.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.