Description

Dl-Isocitric Acid CAS NO 18979-21-0 is a key intermediate in the tricarboxylic acid (TCA) cycle, playing a vital role in cellular energy metabolism. This compound is valued for its biochemical significance and utility as a research standard and analytical reference material. It is essential for laboratories and industries focused on metabolic studies, enzyme research, and the development of diagnostic reagents.

Application

• Biochemical Research & Enzyme Studies: Used as a critical substrate or standard in studying the activity of aconitase and isocitrate dehydrogenase within the TCA cycle.
• Pharmaceutical Intermediates: Serves as a starting material or intermediate in the synthesis of more complex bioactive molecules and potential pharmaceuticals.
• Diagnostic Reagents: Employed in the formulation of clinical diagnostic kits for measuring enzyme activities related to metabolic functions.
• Food & Beverage Analysis: Acts as a reference standard for quality control and authenticity testing in products where citric acid isomers are relevant.
• Cosmetic & Personal Care: Potential use in skincare formulations for its mild exfoliating and antioxidant properties derived from its α-hydroxy acid structure.
• Academic & Teaching Laboratories: Provides a fundamental compound for educational purposes in biochemistry and physiology courses.

Basic Information

Product Name	Dl-Isocitric Acid
CAS No.	18979-21-0
Molecular Formula	C6H8O7
Molecular Weight	192.12 g/mol
Synonyms	DL-Isocitric Acid; (±)-Isocitric Acid; 1-Hydroxypropane-1,2,3-tricarboxylic Acid; 1-Hydroxy-1,2,3-propanetricarboxylic Acid; Iso-citric Acid; all-rac-Isocitric Acid; NSC 3741; 3-Carboxy-2,3-dideoxyglyceric acid-2-carboxylic acid
EINECS	242-746-5

Quality Control

Our Dl-Isocitric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from methods including HPLC, titration, and loss on drying. Our quality commitment supports applications requiring high-purity biochemical reagents and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 10 ppm
Optical Rotation	± 0.05° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.