Description

p-Nitrophenyl 6-Deoxy-α-L-Mannopyranoside is a specialized synthetic glycoside derivative, serving as a critical chromogenic substrate for enzymatic assays. Its core value lies in enabling precise, colorimetric detection and quantification of specific glycosidase enzyme activity. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic reagent manufacturing sectors, where accurate enzyme characterization is paramount.

Application

• Enzymatic Substrate for α-Mannosidase: Primary use as a chromogenic substrate for the detection and kinetic study of α-mannosidase enzymes.
• Biochemical Research & Assay Development: A key reagent in high-throughput screening (HTS) assays and enzyme mechanism studies.
• Diagnostic Kit Manufacturing: Used in the production of diagnostic kits for lysosomal storage disorders, such as α-mannosidosis.
• Quality Control in Biologics: Employed to monitor glycosidase activity during the production and purification of therapeutic proteins and antibodies.
• Microbiology & Glycobiology: A tool for investigating carbohydrate-processing enzymes in various microorganisms and cellular pathways.
• Academic & Industrial R&D: Fundamental research into glycosidase inhibitors and the development of new therapeutic agents.

Basic Information

Product Name	p-Nitrophenyl 6-Deoxy-α-L-Mannopyranoside
CAS No.	18918-31-5
Molecular Formula	C12H15NO7
Molecular Weight	285.25 g/mol
Synonyms	6-Deoxy-α-L-mannopyranosyl p-nitrophenyl; p-Nitrophenyl 6-deoxy-α-L-mannoside; 4-Nitrophenyl 6-deoxy-α-L-mannopyranoside; 6-Deoxy-α-L-mannopyranosyl 4-nitrophenyl; PNPM; pNP-6-deoxy-α-L-mannopyranoside; α-L-6-Deoxymannopyranosyl p-nitrophenyl; 4-Nitrophenyl α-L-6-deoxymannopyranoside
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl 6-Deoxy-α-L-Mannopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.