Description

Californidine is a naturally occurring isoquinoline alkaloid of significant interest in advanced chemical research and development. Its unique structural properties make it a valuable reference standard and a key intermediate for synthesizing novel bioactive compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly those focused on neuropharmacology and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug discovery pipelines.
• Biochemical Research: Serves as a crucial tool compound for studying biological pathways and receptor interactions in neurological research.
• Natural Product Synthesis: Acts as a key chiral building block or intermediate in the total synthesis of complex alkaloids and other natural products.
• Analytical Chemistry: Employed in HPLC, LC-MS, and NMR as a calibration marker or for method validation in complex matrix analysis.
• Academic & Institutional Research: Fundamental for phytochemical studies, pharmacological screening, and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	Californidine
CAS No.	18830-99-4
Molecular Formula	C₂₀H₂₃NO₄
Molecular Weight	341.40 g/mol
Synonyms	Californidine; (+)-Californidine; (S)-Californidine; 6,7,8,13-Tetrahydro-2,3,9,10-tetramethoxy-13-methyl-5H-dibenzo[a,g]quinolizine; 13-Methyl-2,3,9,10-tetramethoxy-6,7,8,13-tetrahydro-5H-dibenzo[a,g]quinolizine; 5H-Dibenzo[a,g]quinolizine, 6,7,8,13-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (S)-; Isoquinoline alkaloid C20H23NO4
EINECS	Contact for details

Quality Control

Our Californidine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.