Description

6-Demethyl 6-o-Benzyl Papaverine is a key pharmaceutical intermediate and synthetic precursor derived from the papaverine alkaloid structure. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly in the field of cardiovascular and smooth muscle pharmacology. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced papaverine analogs and other bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new vasodilators and smooth muscle relaxants.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Process Development: Utilized in scaling up and optimizing synthetic routes for the production of papaverine-related active pharmaceutical ingredients (APIs).
• Biochemical Research: Applied in studies investigating the mechanism of action of phosphodiesterase (PDE) inhibitors.

Basic Information

Product Name	6-Demethyl 6-o-Benzyl Papaverine
CAS No.	18813-62-2
Molecular Formula	C28H27NO5
Molecular Weight	457.52 g/mol
Synonyms	6-O-Benzyl-6-demethylpapaverine; 6-Benzyloxy-1-veratrylisoquinoline; 1-(3,4-Dimethoxybenzyl)-6-(phenylmethoxy)-7-methoxyisoquinoline; 6-O-Benzylpapaverine derivative; Papaverine, 6-demethyl-6-O-benzyl-; 6-Benzyloxypapaverine analog
EINECS	Contact for details

Quality Control

Our 6-Demethyl 6-o-Benzyl Papaverine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.