Description

(16R)-6β,17-Epoxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester CAS NO 18783-45-4 is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral intermediate and building block for the development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural products and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex alkaloid-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies in the discovery of new neuroactive compounds.
• Asymmetric Synthesis: Employed in advanced organic synthesis to introduce specific stereochemistry and complex molecular frameworks.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Natural Product Synthesis: A vital intermediate in the total or semi-synthesis of sarpagine and related indole alkaloids.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzyme or receptor targets.

Basic Information

Product Name	(16R)-6β,17-Epoxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester
CAS No.	18783-45-4
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Methyl (16R)-6β,17-epoxy-1-methylsarpagan-16-carboxylate; 1-Methylsarpagan-16-carboxylic acid, 6β,17-epoxy-, methyl ester, (16R)-; 16R-6β,17-Epoxy-1-methylsarpagan-16-carboxylic acid methyl ester; Sarpagine derivative; Indole alkaloid intermediate; 18783-45-4; (16R)-6β,17-Epoxy-1-methylsarpagan-16-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (16R)-6β,17-Epoxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.