Description

2,3-Dihydroxypropyl (9Z,12Z,15Z)-9,12,15-octadecatrienoate is a structured lipid derivative of α-linolenic acid (ALA), an essential ω-3 fatty acid. This compound is valued for its bifunctional chemical structure, combining the bioactive properties of ALA with a hydrophilic glycerol backbone, which enhances its utility in advanced formulations. It serves as a critical intermediate and functional ingredient for manufacturers in the nutraceutical, pharmaceutical, and high-end cosmetic industries seeking to incorporate stabilized ω-3 moieties into their products.

Application

• Nutraceutical Intermediate: Used in the synthesis of specialized lipid supplements and phospholipid conjugates designed for enhanced bioavailability of ω-3 fatty acids.
• Pharmaceutical Excipient: Acts as a functional carrier or emulsifying agent in lipid-based drug delivery systems (e.g., self-emulsifying drug delivery systems - SEDDS) to improve the solubility of poorly water-soluble APIs.
• Cosmetic Actives: Incorporated into anti-aging and skin-barrier repair formulations for its moisturizing properties and potential skin-beneficial effects derived from ALA.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies, lipid metabolism research, and the development of analytical methods for complex lipids.
• Functional Food Additive: Employed in the fortification of foods and beverages with stabilized, bioavailable ω-3 fatty acids without compromising taste or shelf-life.
• Liposome & Nanocarrier Production: A key component in the fabrication of liposomes and nanoparticles for targeted nutrient or drug delivery applications.

Basic Information

Product Name	2,3-Dihydroxypropyl (9Z,12Z,15Z)-9,12,15-octadecatrienoate
CAS No.	18465-99-1
Molecular Formula	C21H36O5
Molecular Weight	368.51 g/mol
Synonyms	Monoacylglycerol of α-Linolenic Acid; Glyceryl α-Linolenate; (9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid, 2,3-Dihydroxypropyl Ester; α-Linolenoyl Glycerol; Glycerol Mono-α-Linolenate; 1-Mono-α-Linolenin; MAG (18:3 n-3); 1-Glyceryl α-Linolenate
EINECS	242-347-0

Quality Control

Our production of 2,3-Dihydroxypropyl (9Z,12Z,15Z)-9,12,15-octadecatrienoate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity suitable for demanding applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and relevant industry standards for pharmaceutical and nutraceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. The material is easily oxidized and moisture-sensitive; therefore, the container should be opened minimally and under controlled, dry conditions. Keep away from heat and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Acid Value	≤ 5.0 mg KOH/g
Peroxide Value	≤ 5.0 meq/kg
Water Content (KF)	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.