Description

(S)-12-Hydroxyoctadecanoic Acid is a high-purity, chiral hydroxy fatty acid with significant value in advanced organic synthesis and materials science. Its enantiomeric purity and specific hydroxyl group positioning make it a crucial building block for synthesizing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients, chiral ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of bioactive molecules, prostaglandins, and other therapeutic agents requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where enantioselectivity impacts efficacy and environmental safety.
• Specialty Polymer & Material Science: Serves as a monomer or modifier for creating functional polymers, liquid crystals, and biodegradable materials with tailored properties.
• Cosmetic & Personal Care Ingredients: Potential use in the synthesis of specialty esters and emulsifiers for high-end skincare formulations.
• Chemical Research & Development: A valuable standard and reagent in academic and industrial R&D for studying lipid metabolism, asymmetric synthesis, and chiral recognition.
• Flavor & Fragrance Industry: Intermediate for the synthesis of chiral lactones and other compounds contributing to specific aroma profiles.

Basic Information

Product Name	(S)-12-Hydroxyoctadecanoic Acid
CAS No.	18417-00-0
Molecular Formula	C₁₈H₃₆O₃
Molecular Weight	300.48 g/mol
Synonyms	(S)-12-Hydroxystearic Acid; (12S)-12-Hydroxyoctadecanoic Acid; (S)-12-Hydroxy Stearic Acid; L-12-Hydroxystearic Acid; (S)-(-)-12-Hydroxystearic Acid; 12-Hydroxyoctadecanoic Acid, (S)-; 12(S)-HSA; 12-Hydroxy Stearic Acid (S-enantiomer)
EINECS	242-307-1

Quality Control

Our (S)-12-Hydroxyoctadecanoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, purity, and specific rotation. Our quality commitment supports applications requiring stringent material consistency, from research to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent absorption of water vapor. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	78 - 82 °C
Specific Rotation [α]₂₀D	-2.0° to -4.0° (c=1 in CHCl₃)
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.