Description

Hodgkinsine CAS NO 18210-71-4 is a complex monoterpene indole alkaloid of significant interest in advanced organic synthesis and pharmacological research. This compound serves as a valuable chemical reference standard and a sophisticated building block for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in neurological studies and the synthesis of complex natural product derivatives.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified material for analytical method development, validation, and quality control in research laboratories.
• Medicinal Chemistry Research: Serves as a key intermediate or lead compound in the synthesis and structure-activity relationship (SAR) studies of new therapeutic agents.
• Neurological Research: Investigated for its biological activity in preclinical studies related to neurological pathways and receptor interactions.
• Natural Product Synthesis: Employed as a challenging synthetic target or a starting material for the total synthesis of complex indole alkaloids.
• Biochemical Research: Used in studies to understand enzyme inhibition and other biochemical mechanisms at a molecular level.

Basic Information

Product Name	Hodgkinsine
CAS No.	18210-71-4
Molecular Formula	C43H52N4O4
Molecular Weight	688.91 g/mol
Synonyms	Hodgkinsine; Hodgkinsin; Hodgkinsine (alkaloid); 3,4,5,6-Tetradehydro-18,19-didehydro-10,17-secocorynan-16-carboxylic acid, 17,18-epoxy-10,19-lactone, methyl ester, (16α)-; Methyl (16α)-17,18-epoxy-3,4,5,6-tetradehydro-18,19-didehydro-10,17-secocorynan-16-carboxylate 10,19-lactone
EINECS	Contact for details

Quality Control

Our Hodgkinsine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods such as HPLC and NMR. We support compliance with GLP and GMP guidelines where required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term stability, consider storage under inert atmosphere at lower temperatures (e.g., -20°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.