Description

16-Hydroxyestrone is a significant metabolite of estrone, playing a crucial role in estrogen metabolism pathways. This compound is essential for researchers and developers in the life sciences sector, providing a key intermediate for studying hormonal activity and metabolic processes. It is primarily utilized in pharmaceutical R&D, clinical diagnostics, and as a reference standard in analytical chemistry.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate and reference standard in the study of estrogen metabolism, drug discovery, and metabolic pathway analysis.
• Clinical Diagnostics: Used in the development and calibration of assays for quantifying estrogen metabolites in biological samples for clinical research.
• Biochemical Studies: Employed as a reagent in enzymatic studies and investigations into steroid hormone biosynthesis and catabolism.
• Reference Standard: Acts as a high-purity certified reference material (CRM) for quality control in analytical laboratories using techniques like HPLC, LC-MS, or GC-MS.
• Academic Research: Utilized in university and institutional labs for fundamental endocrinology and biochemistry research projects.

Basic Information

Product Name	16-Hydroxyestrone
CAS No.	18186-49-7
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	16α-Hydroxyestrone; 1,3,5(10)-Estratriene-3,16α-diol-17-one; 16α-Hydroxy-1,3,5(10)-estratriene-3,17-dione; Estra-1,3,5(10)-triene-3,16α-diol-17-one; 16α-Hydroxyestra-1,3,5(10)-triene-3,17-dione; 16-OHE1; 16α-OHE1
EINECS	Contact for details

Quality Control

Our 16-Hydroxyestrone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatography, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.