Description

Ethyl B-D-Glucuronide is a high-purity biochemical standard and analytical reference material. This compound is essential for research and quality control in analytical chemistry, serving as a critical standard for the detection and quantification of glucuronide metabolites. It is primarily utilized by pharmaceutical R&D laboratories, forensic toxicology units, and contract research organizations (CROs) for method development and validation. Its consistent quality ensures reliable and reproducible results in sensitive analytical applications.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for calibrating instruments and validating analytical methods in HPLC, LC-MS, and GC-MS.
• Pharmaceutical Metabolism Studies: Used in ADME (Absorption, Distribution, Metabolism, and Excretion) research to study drug conjugation pathways and glucuronidation kinetics.
• Forensic and Clinical Toxicology: Critical for the accurate identification and quantification of ethyl glucuronide (EtG), a direct biomarker for ethanol consumption, in hair, urine, and blood analysis.
• Enzymology Research: Serves as a substrate or standard in studies involving UDP-glucuronosyltransferase (UGT) enzyme activity and inhibition.
• Biochemical Synthesis: Acts as a key intermediate or building block in the synthetic pathways of more complex glycosides or labeled compounds.
• Quality Control (QC) Testing: Employed by manufacturers of diagnostic kits and reagents to ensure batch-to-batch consistency and performance.

Basic Information

Item	Details
Product Name	Ethyl B-D-Glucuronide
CAS No.	17685-04-0
Molecular Formula	C8H14O7
Molecular Weight	222.19 g/mol
Synonyms	Ethyl β-D-Glucopyranosiduronic Acid; Ethyl Glucuronide; EtG; Ethyl D-Glucuronide; β-D-Glucopyranosiduronic Acid, Ethyl Ester; Ethyl-β-D-glucopyranosiduronate; 1-O-Ethyl-β-D-glucuronic Acid; 17685-04-0
EINECS	Contact for details

Quality Control

Every batch of Ethyl B-D-Glucuronide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use as a reference material, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting batch-specific results for identity, assay, purity, and related substances. Our quality commitment ensures compliance with the rigorous standards expected in pharmaceutical and forensic analysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.