Description

Dihydroergocristine is a semi-synthetic ergot alkaloid derivative, known for its high purity and specific biological activity. This compound is critical for pharmaceutical research and development, particularly in the study of neurological and cardiovascular systems. It is primarily utilized by research institutions and pharmaceutical manufacturers developing advanced therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthesis of complex pharmaceutical compounds targeting specific receptor pathways.
• Neurological Research: Employed in preclinical studies to investigate its effects on dopaminergic and serotonergic systems.
• Vasoconstrictive Studies: Applied in cardiovascular research to study its impact on blood vessel tone and related physiological mechanisms.
• Biochemical Assay Development: Utilized as a key reagent in developing high-throughput screening assays for drug discovery.
• Academic Research: Supports chemical and pharmacological research in university and institutional laboratories worldwide.

Basic Information

Product Name	Dihydroergocristine
CAS No.	17479-19-5
Molecular Formula	C35H41N5O5
Molecular Weight	611.73 g/mol
Synonyms	Dihydroergocristine; DHEC; 9,10-Dihydroergocristine; Dihydroergokristine; (6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-10b-Hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide; Dihydroergocristine Mesylate (salt form); CAS 17479-19-5
EINECS	Contact for details

Quality Control

Our Dihydroergocristine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.