Description

Udp-Glucosamine CAS NO 17479-04-8 is a key nucleotide sugar derivative, serving as an essential biochemical precursor in the biosynthesis of glycosaminoglycans, glycoproteins, and glycolipids. Its primary commercial value lies in its critical role as a substrate for glycosyltransferases in enzymatic synthesis and research applications. This high-purity biochemical is indispensable for pharmaceutical R&D, biotechnology companies, and academic institutions focused on carbohydrate chemistry, glycobiology, and the development of novel therapeutic agents.

Application

• Enzymatic Synthesis Substrate: Critical reagent for in vitro glycosylation reactions catalyzed by glycosyltransferases to produce complex oligosaccharides and glycoconjugates.
• Glycobiology Research: Used in studies investigating biosynthetic pathways of heparan sulfate, hyaluronic acid, and other glycosaminoglycans (GAGs).
• Pharmaceutical Intermediate: Serves as a building block in the research and development of carbohydrate-based drugs and diagnostics.
• Biochemical Assay Standard: Employed as a reference standard in HPLC, LC-MS, and enzymatic assays to quantify enzyme activity or reaction products.
• Cell Culture & Metabolic Studies: Utilized in cell-based research to study cell surface glycosylation and metabolic labeling.
• Diagnostic Kit Manufacturing: A component in the production of diagnostic kits for enzymes involved in carbohydrate metabolism.

Basic Information

Product Name	Udp-Glucosamine
CAS No.	17479-04-8
Molecular Formula	C17H27N3O17P2
Molecular Weight	607.35 g/mol
Synonyms	UDP-GlcN; Uridine 5'-diphosphoglucosamine; UDP-D-glucosamine; Uridine diphosphate glucosamine; UDP-N-acetylglucosamine precursor; Uridine diphosphoglucosamine; 5'-Uridylic acid, mono[2-(acetylamino)-2-deoxy-D-glucopyranosyl] ester, dihydrogen phosphate (ester); GlcNAc-PP-Uridine
EINECS	Contact for details

Quality Control

Our Udp-Glucosamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets stringent specifications for research and enzymatic use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay results, and absence of critical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.