Description

p-Nitrophenyl-α-D-Maltoside is a chromogenic substrate specifically designed for the detection and quantification of α-glucosidase activity. This compound matters because it provides a highly sensitive and reliable method for enzymatic analysis, producing a yellow-colored p-nitrophenol upon hydrolysis that is easily measured spectrophotometrically. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries who require precise enzyme activity measurements for drug discovery, biochemical research, and diagnostic kit development.

Application

• Enzyme Assay Substrate: Primary substrate for the spectrophotometric assay of α-glucosidase and related enzymes.
• Diagnostic Reagent Manufacturing: Key component in the production of clinical diagnostic kits for metabolic disorders like Pompe disease or diabetes.
• Biochemical Research: Used in studies of carbohydrate metabolism, enzyme kinetics, and inhibitor screening.
• Pharmaceutical Quality Control: Employed in potency testing and stability studies of enzyme-based therapeutics.
• Microbiology: Applied in research for identifying bacterial or fungal species based on specific glycosidase activity.
• Food & Beverage Analysis: Useful in monitoring enzymatic processes in food production, such as starch conversion.

Basic Information

Product Name	p-Nitrophenyl-α-D-Maltoside
CAS No.	17400-77-0
Molecular Formula	C18H25NO13
Molecular Weight	463.39 g/mol
Synonyms	4-Nitrophenyl α-D-maltoside; p-Nitrophenyl α-maltoside; α-D-Glucopyranosyl-(1→4)-α-D-glucopyranoside 4-nitrophenyl; 4-Nitrophenyl α-D-glucopyranosyl-(1→4)-α-D-glucopyranoside; PNPG2; PNP-α-Maltoside; α-Glucosidase Substrate; 4-Nitrophenyl-α-maltoside
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl-α-D-Maltoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive enzymatic assays. Each lot undergoes rigorous analytical testing, including HPLC for purity verification and spectrophotometric checks for functional performance. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 2.0%
Specific Rotation	Contact for details
Absorbance (Lambda max)	Contact for details
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.