Description

1-(Hydroxymethyl)-β-Carboline is a heterocyclic organic compound belonging to the β-carboline alkaloid family, characterized by a hydroxymethyl substituent at the 1-position. This structural motif is of significant interest in medicinal chemistry and biochemical research due to its potential as a versatile synthetic intermediate and a core scaffold for pharmacologically active molecules. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of novel compounds for neurological and oncological studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Biochemical Research: Used as a reference standard or precursor in studies investigating the biological activity of β-carboline alkaloids, such as MAO inhibition or interaction with benzodiazepine receptors.
• Medicinal Chemistry: Acts as a core scaffold for the development and structure-activity relationship (SAR) studies of potential therapeutic agents.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex, high-value specialty chemicals for research and development.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and alkaloid pharmacology.

Basic Information

Product Name	1-(Hydroxymethyl)-β-Carboline
CAS No.	17337-22-3
Molecular Formula	C₁₂H₁₀N₂O
Molecular Weight	198.22 g/mol
Synonyms	1-(Hydroxymethyl)-9H-pyrido[3,4-b]indole; Norharman-1-methanol; 1-Hydroxymethyl-β-carboline; 1-Hydroxymethyl-9H-pyrido[3,4-b]indole; β-Carbolin-1-ylmethanol; 1-Methanol-β-carboline
EINECS	Contact for details

Quality Control

Our 1-(Hydroxymethyl)-β-Carboline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.