Description

Pretazettine is a natural alkaloid compound of significant interest in advanced pharmaceutical research and development. Its unique molecular structure makes it a valuable reference standard and a key intermediate for synthesizing novel bioactive molecules. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on oncology and neurological drug discovery programs.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory submissions in drug development.
• Medicinal Chemistry Research: Serves as a crucial intermediate or lead compound for the synthesis of novel analogs with potential therapeutic activity.
• Biological Activity Screening: Employed in high-throughput screening (HTS) assays to evaluate interactions with various biological targets, particularly in cancer and neurological research.
• Academic and R&D Laboratories: Utilized in university and institutional research for studying alkaloid biosynthesis, structure-activity relationships (SAR), and natural product chemistry.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the multi-step synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	Pretazettine
CAS No.	17322-84-8
Molecular Formula	C₁₈H₂₁NO₅
Molecular Weight	331.37 g/mol
Synonyms	Pretazettine; 6-Hydroxy-1,2,3,4,4a,5,6,11b-octahydro-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-9-ol; Narciclasine-4-O-β-D-glucopyranoside (aglycone); Amaryllidaceae Alkaloid; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Pretazettine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for research materials. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.