Description

Oxyluciferin is a key organic heterotricyclic compound and the primary light-emitting product of the bioluminescent reaction catalyzed by luciferase enzymes. This compound matters as a critical reference standard and research tool for studying bioluminescence mechanisms, assay development, and enzyme kinetics. It is essential for researchers and manufacturers in the fields of life science research, pharmaceutical screening, and diagnostic assay development who require high-purity biochemicals for reliable and reproducible results.

Application

• Bioluminescence Research: Fundamental studies on luciferase enzyme mechanisms, kinetics, and light emission pathways.
• Assay Development & Validation: Serves as a critical reference standard and control in the development and optimization of bioluminescent assays for high-throughput screening (HTS).
• Pharmaceutical & Drug Discovery: Used in cell-based reporter assays to study gene expression, protein-protein interactions, and compound efficacy in drug discovery pipelines.
• Diagnostic Reagents: A component in the development of sensitive diagnostic kits and biosensors that utilize bioluminescent detection.
• Enzyme Characterization: Employed to characterize the activity, specificity, and inhibition of recombinant and native luciferase enzymes.
• Biochemical Education: Used in academic settings for teaching advanced concepts in enzymology and bioluminescence.

Basic Information

Item	Detail
Product Name	Oxyluciferin
CAS No.	17297-78-8
Molecular Formula	C13H9N2O3S2
Molecular Weight	305.35 g/mol
Synonyms	D-(-)-2-(6'-Hydroxy-2'-benzothiazolyl)-2-thiazoline-4-carboxylic Acid; D-(-)-Luciferin; Oxyluciferin (D-form); D-OxyLH2; 2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic Acid; Firefly Luciferin Oxidation Product; (4S)-2-(6-Hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Oxyluciferin is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While not intended for human therapeutic use, our quality systems ensure the material meets the stringent requirements for biochemical and diagnostic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.