Description

Isotazettine, 8-o-Methyl- is a specific alkaloid derivative of the tazettine family, identified by the CAS registry number 17245-21-5. This compound is valued for its defined chemical structure, which serves as a critical intermediate and reference standard in advanced organic synthesis and pharmacological research. It is primarily sought by professionals in the pharmaceutical development, agrochemical research, and fine chemical synthesis sectors who require high-purity, structurally characterized building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs) and therapeutic agents.
• Biochemical Research: Used as a reference standard and probe in studying alkaloid biosynthesis pathways and biological activity.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex molecular architectures in academic and industrial laboratories.
• Agrochemical Development: Investigated as a potential intermediate for creating new crop protection agents with specific modes of action.
• Analytical Standard: Employed in analytical methods such as HPLC and LC-MS for method development, validation, and quality control of related substances.

Basic Information

Product Name	Isotazettine, 8-o-Methyl-
CAS No.	17245-21-5
Molecular Formula	C18H21NO5
Molecular Weight	331.37 g/mol
Synonyms	8-O-Methylisotazettine; 8-O-Methyl-Isotazettine; Isotazettine 8-Methyl Ether; 3,4,12,12a-Tetrahydro-7-hydroxy-6,8-dimethoxy-3-methyl-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-1-one; (12aS)-3,4,12,12a-Tetrahydro-7-hydroxy-6,8-dimethoxy-3-methyl-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-1-one
EINECS	Contact for details

Quality Control

Our Isotazettine, 8-o-Methyl- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.