Description

11B-Hydroxyetiocholanolone Glucuronide is a specific glucuronide conjugate of a key steroid metabolite, representing a high-purity reference standard and biochemical intermediate. This compound is critical for analytical and research applications requiring precise quantification and metabolic pathway studies. It is primarily utilized by pharmaceutical R&D laboratories, clinical diagnostic manufacturers, and academic institutions focused on endocrinology and steroid metabolism.

Application

• Reference Standard for Analytical Chemistry: Used as a certified standard for the calibration and validation of LC-MS/MS, HPLC, and GC-MS systems in quantitative bioanalysis.
• Biochemical Research: Serves as a crucial substrate or metabolite in studies investigating steroid hormone metabolism, conjugation pathways, and enzyme kinetics.
• Diagnostic Kit Development: Employed in the manufacturing and quality control of immunoassays and other diagnostic tests for hormonal disorders.
• Pharmaceutical Impurity Profiling: Acts as a known impurity or degradation product standard in the development and stability testing of steroid-based pharmaceuticals.
• Metabolite Identification: Essential for the structural confirmation and identification of metabolites in drug discovery and development (DMPK studies).
• Clinical Toxicology: Used in laboratories specializing in sports anti-doping testing and forensic analysis for accurate steroid profiling.

Basic Information

Product Name	11B-Hydroxyetiocholanolone Glucuronide
CAS No.	17181-15-6
Molecular Formula	C27H42O9
Molecular Weight	510.62 g/mol
Synonyms	11β-Hydroxyetiocholanolone Glucuronide; 11β-Hydroxy-3α-hydroxy-5β-androstan-17-one 3-Glucuronide; Etiocholanolone-11β-ol Glucuronide; 5β-Androstane-3α,11β-diol-17-one 3-Glucuronide; 11β-Hydroxyetiocholanolone 3α-D-Glucopyranosiduronic Acid; 11β-Hydroxy-5β-androstane-3α,17β-diol-17-one 3-Glucuronide; 11β-OH-Etio-G; A Steroid Metabolite Glucuronide
EINECS	Contact for details

Quality Control

Our 11B-Hydroxyetiocholanolone Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for use as a reference material. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.