Description

(17S,20S)-17-Methyl-20-[(2S,5S)-5-Methyl-2-Piperidyl]-18-Norpregna-5,12-Diene-3β,16β-Diol is a high-purity, structurally complex steroid derivative of significant interest in advanced pharmaceutical research and development. Its unique molecular architecture makes it a valuable intermediate or reference standard for synthesizing novel therapeutic agents and conducting structure-activity relationship (SAR) studies. This compound is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure product identity and purity.
• Biochemical Research: Serves as a tool compound for investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding affinities in vitro.
• Academic & Discovery Chemistry: Enables medicinal chemists to explore new chemical spaces and develop proprietary compound libraries for high-throughput screening.
• Metabolite Synthesis: Used in the preparation of potential drug metabolites for pharmacokinetic and toxicological studies.

Basic Information

Product Name	(17S,20S)-17-Methyl-20-[(2S,5S)-5-Methyl-2-Piperidyl]-18-Norpregna-5,12-Diene-3β,16β-Diol
CAS No.	17155-31-6
Molecular Formula	C27H41NO2
Molecular Weight	411.62 g/mol
Synonyms	17-Methyl-20-[(2S,5S)-5-methyl-2-piperidyl]-18-norpregna-5,12-diene-3β,16β-diol; (17S,20S)-17-Methyl-20-[(2S,5S)-5-methylpiperidin-2-yl]-18-norpregna-5,12-diene-3β,16β-diol; 18-Nor-17-methylpregna-5,12-diene-3β,16β-diol derivative; Steroid-piperidine hybrid; 17155-31-6; 3β,16β-Dihydroxy-17-methyl-20-[(2S,5S)-5-methyl-2-piperidyl]-18-norpregna-5,12-diene
EINECS	Contact for details

Quality Control

Every batch of (17S,20S)-17-Methyl-20-[(2S,5S)-5-Methyl-2-Piperidyl]-18-Norpregna-5,12-Diene-3β,16β-Diol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated research environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the contents from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.